Endocrine Abstracts

JOINT1465

Background: The detection of adrenal tumors has become increasingly common due to advances in imaging technologies, particularly computed tomography (CT). Adrenal tumors, which occur in 4-10% of the general population, are often found incidentally and tend to be asymptomatic. However, certain tumors can present significant clinical challenges, especially those with malignant potential or associated endocrine dysfunction. These tumors vary widely in histopathological types, from benign adenomas to more aggressive conditions like adrenocortical carcinoma and metastatic lesions.

Case Presentation: This report discusses six cases of adrenal tumors in Caucasian patients, including five females and one male. The tumors included ganglioneuroma, traumatic adrenal hematoma with fibrosis, pheochromocytoma, and adrenocortical carcinoma. Clinical presentations varied, with some patients experiencing hormone overproduction symptoms, while others were asymptomatic and discovered incidentally during imaging for unrelated reasons. Surgical intervention was performed in all cases, and diagnoses were confirmed via histopathological examination postoperatively. These cases underscore the clinical diversity of adrenal tumors and the complexities involved in their diagnosis and management.

Conclusions: The rising incidence of adrenal tumor detection, particularly incidentalomas, highlights the importance of comprehensive evaluation to differentiate between benign and malignant tumors. Hormonal imbalances caused by adrenal tumors can lead to significant endocrine disorders, while malignant tumors present serious health risks. A multidisciplinary approach that includes imaging, clinical evaluation, and histological analysis is critical for effective management and improved patient outcomes. Early diagnosis and treatment are essential, especially considering the potential for malignancy and endocrine complications. These cases also emphasize the need for a tailored approach in treating diverse patient populations, including Caucasians.

Key Words: adrenal tumors, incidentalomas, endocrine disorders, adrenocortical carcinoma, ganglioneuroma, pheochromocytoma