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Endocrine Abstracts (2025) 110 EP645 | DOI: 10.1530/endoabs.110.EP645

1Habib Bourguiba University Hospital, Nuclear Medicine Department, Sfax, Tunisia; 2Hedi Chaker University Hospital, Sfax, Tunisia


JOINT3841

18F-FDG PET/CT is widely used in oncology for staging and monitoring various malignancies, but it can also reveal unexpected findings, including thyroid nodules. Incidental detection of papillary thyroid carcinoma (PTC) on PET imaging is uncommon and often requires further evaluation. We report the case of a 50-year-old woman undergoing treatment for follicular lymphoma. As part of the initial staging workup, an 18F-FDG PET/CT was performed, revealing a hypermetabolic nodule in the upper right thyroid lobe. A cervical ultrasound confirmed the presence of a suspicious thyroid nodule, and a fine-needle aspiration biopsy was performed. Cytological analysis was suggestive of papillary thyroid carcinoma (Bethesda V). Given these findings, the patient underwent total thyroidectomy with bilateral recurrent lymph node dissection. Histopathological analysis confirmed a 1.3 cm papillary thyroid carcinoma with focal capsular invasion and clear surgical margins. Lymph node dissection was positive on the left side. Consequently, the patient was scheduled for radioactive iodine therapy. This case highlights the role of 18F-FDG PET/CT in detecting incidental thyroid malignancies in patients with other primary cancers. It underscores the importance of further evaluation of hypermetabolic thyroid nodules to ensure timely diagnosis and appropriate management.

Volume 110

Joint Congress of the European Society for Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE) 2025: Connecting Endocrinology Across the Life Course

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