ECEESPE2025 ePoster Presentations Thyroid (198 abstracts)
Synchronous papillary thyroid cancer and malignant neoplasms: Hodgkin lymphoma and nasopharyngeal carcinoma
Malika El Omri 1 , Nawress Thabet 2 , Mouna Belakhdher 1 , Jihene Houas 1 , Abir Meherzi 1 , Monia Ghammam 1 , Hamza Elfekih 3 , Wassim Kermani 1 & Mohamed Abdelkafi 1
1Farhat Hached Hospital, Department of ENT and Head and Neck Surgery, Sousse, Tunisia; 2Farhat Hached University Hospital, ENT Department, Sousse, Tunisia; 3Farhat Hached Hospital, Department of Endocrinology, Sousse, Tunisia.
JOINT679
Objectives: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Its co-occurrence with Hodgkin’s lymphoma (HL) and nasopharyngeal undifferentiated carcinoma (UCNT) is extremely rare. The aim of this study is to investigate the clinical characteristics and treatment challenges associated with this unusual situation.
Methods: We conducted a retrospective analysis of three cases of synchronous tumours involving the thyroid gland, which were reported in our department.
Results: This report presents the cases of three female patients aged 27, 51, and 70 years, respectively. One patient presented with fever and night sweats, another with a suspicious thyroid nodule, and the third with multiple cervical lymph nodes and unilateral epistaxis. Physical examination revealed cervical lymphadenopathies in all three cases, an indurated thyroid nodule in one case, and a suspicious tumoral process in the nasopharynx in another case. All patients underwent a neck ultrasound. Two patients underwent a body scan in addition to a nasopharyngeal scan. All patients underwent a thyroid fine needle aspiration, with one patient also receiving a nasopharyngeal biopsy and two patients receiving an adenectomy. The diagnosis of papillary thyroid carcinoma (PTC) was made in two cases with Hodgkin’s lymphoma (HL) and in one case with undifferentiated carcinoma (UCNT). Initially, all three patients underwent total thyroidectomy with lymph node dissection. Subsequent treatment for the other neoplasms after surgery included chemotherapy for the two cases of Hodgkin’s lymphoma and radiotherapy associated with chemotherapy for the undifferentiated carcinoma of the nasopharynx. The radioactive iodine treatment was delayed following the management of synchronous cancer.
Conclusion: the synchronous occurrence of differentiated thyroid cancer and malignant tumors presents a significant diagnostic and treatment challenge. It is important to note that the presence of a suspicious lymph node in papillary thyroid carcinoma may indicate the presence of other concurrent head and neck malignant tumors.
Volume 110
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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