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Endocrine Abstracts (2025) 110 EP1002 | DOI: 10.1530/endoabs.110.EP1002

1National Institute of Nutrition and Food Technology, Department Of Nutritional Diseases D, Tunis, Tunisia; 2National Institute of Nutrition and Food Technology, Department of Nutritional Diseases D, Tunis, Tunisia


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Introduction: Malnutrition is a common and insidious problem that often goes underdiagnosed. The aim of our study was to analyze the clinical and biological profiles of malnourished patients.

Materials and Methods: A cross-sectional study was conducted, including 35 patients followed for underweight in the outpatient department of the national institute of Nutrition. The following phenotypic criteria were collected: BMI, muscle strength (MS), and weight loss (WL).

Results: The mean age was 35.14 ± 15.95 years, with a predominance of females (82.9%). The mean BMI was 17.51 ± 4.3 kg/m2. The average muscle strength (MS) and weight loss (WL) were 23.27 ± 10.1 kg and 15.83 ± 9.63%, respectively. The prevalence of malnutrition was 65.71%, according to the HAS recommendations, which include at least one phenotypic criterion and one etiological criterion. Severe malnutrition was observed in 56.52% of cases. The mean levels of albumin, hemoglobin, calcium, and magnesium were 41.73 ± 4.7 g/L; 11.98 ± 1.88 g/dl; 2.35 ± 0.11 mmol/l, and 0.8 ± 0.07 mmol/l, respectively. Hypoalbuminemia, anemia, hypocalcemia, and hypomagnesemia were noted in 9.1%, 45.71%, 5.7%, and 20% of cases, respectively. Malnutrition was associated with weight loss (P = 0.001). Anemia was linked to a reduction in muscle strength (P = 0.03). No correlations were found between magnesium levels and the different anthropometric parameters, nor between calcium levels and the parameters.

Conclusion: Malnutrition often presents subtly, underscoring the importance of early detection and heightened awareness among healthcare providers..

Volume 110

Joint Congress of the European Society for Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE) 2025: Connecting Endocrinology Across the Life Course

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