Endocrine Abstracts

JOINT128

Introduction: NASH is an increasingly relevant finding in the pediatric population affected by obesity. In adults, the evolution of this steatosis towards fibrosis and correlation with metabolic syndrome is increasingly significant. The existence of a rapid and validated in-office screening tool would be very useful.

Main objective: To evaluate whether the measurement of intraperitoneal fat measured through nutritional ultrasound allows for the diagnosis of non-fatty hepatic steatosis or metabolic risk in overweight/obese patients. Establish if there is any type of correlation between abdominal fat measurements obtained by nutritional ultrasound and those obtained in routine clinical practice of these patients using liver ULTRASOUND if this is performed within routine clinical practice.

Material and Methods: Patients who attend of Endocrinology due to overweight. BMI >2 SDS. MINDRAY Z50 ULTRASOUNDGRAPH. (Hamagawa technique) through an abdominal adipose ultrasound study (Superficial subepidermal fat – stored, deep and intraperitoneal energy-risk in adults for NASH). Comparison with ECO performed by expert radiologists.

Results: Study on 150 patients with deep ECHO by an expert pediatric radiologist and nutritional ECHO. NASH 90/150 (60%). Distribution mild 72/150 (48%), moderate 14/150 (9%) and severe 3/150 (1.7%). A Mann-Whitney U test was performed on 150 patients. The results showed that the cut-off point that presents confirm a positive correlation between NASH YES/NO would be an average of 0.82 cm CI[ 0.70-0.94]95% using Mann-Whitney U. Children who lost weight (fat mass by impedanciometer TANITA) after unless 12 mouths has measures of pre-peritoneal fat less than children who not.

Conclusions: There is a significant number of pediatric cases with NASH in the obese population. The use of rapid nutritional ECO (preperitoneal fat) is related by a linear and positive correlation with the presence of NASH studied by traditional ECO in expert hands.