ECEESPE2025 ePoster Presentations Multisystem Endocrine Disorders (51 abstracts)
Growth and puberty of children living HIV/AIDS in a reference service in northeastern brazil
carla cilene nascimento castro 1 , Wellington Rodrigo de Melo 1 , Marcos Antonio Pereira 1 , Maria dos Remédios Branco 1 , Rossana Azulay 1 , Jairo Morais 2 , Carlos Corbett 3 , Mônica Gama 1,3 & Débora Lago 1,3
1Universidade Federal do Maranhão, São Luis, Brazil; 2UNILAB, Ceará, Brazil; 3Universidade de São Paulo - USP, Patologia, São Paulo, Brazil
JOINT2905
Human immunodeficiency virus (HIV) infection is a highly relevant pediatric pathology worldwide. Due to metabolic alterations inherent to the disease and factors related to treatment, children living with HIV/AIDS may present growth alterations and delayed pubertal development. Early introduction of antiretroviral therapy (ART) has increased the survival rate of this population and improved the anthropometric prognosis of infected children and adolescents. The study is justified by the scarcity of current data on the subject of the global pediatric population and aims to evaluate the growth and pubertal development of children and adolescents living with HIV/AIDS followed in a specialized service in Maranhão (Northeast Brazil). This is a cross-sectional observational study that has included, to date, 76 patients, followed at the service between October 2022 and July 2024 and evaluated by a single observer. Descriptive analysis was carried out using the SPSS version 20.0 program. It was observed that the average age was 8 years, the majority were brown, with an age at diagnosis of less than one year and an average use of ART of 5.3 years. Appropriate z-score weight for age was observed in 64.5% of the population, appropriate z-score height for age in 82.9% and appropriate z-score BMI z-score in 76.3% of cases. Of the individuals evaluated, 52 (68.4%) were in the pre-pubertal phase, while 24 were in the puberty phase. Of the 24 patients already in puberty, 21 (87.5%) had normal puberty, two had precocious puberty and one had delayed puberty. For females, the average age at the onset of thelarche was 8.10 years ± 1.7, pubarche was 10 years ± 0.8, and menarche was 11.6 years ± 0.4. For males, the average age of the gonadarche was 11. 6 years ± 1.4 and that of the pubarche was 12 years ± 1.2. This study identified that the majority of children and adolescents living with HIV presented adequate growth and pubertal development.
Volume 110
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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