ECEESPE2025 ePoster Presentations Adrenal and Cardiovascular Endocrinology (170 abstracts)
1Hedi Chaker University Hospital, Department of Endocrinology, Sfax, Tunisia
JOINT1513
Introduction: Adrenal ganglioneuroma (AG) is a rare tumor comprising less than 5% of all adrenal masses. Its morphological and radiological characteristics are nonspecific, which can complicate the diagnostic process. We report the case of an AG in a 16-year-old girl.
Case Report: A patient with no medical history was referred for evaluation of an adrenal mass. She reported paroxysmal lumbar pain over the past 4 years. Clinical examination was unremarkable, laboratory tests were notable only for iron deficiency anemia. Computed tomography revealed a right adrenal mass extending across the midline, measuring 83×39×64mm, with a density of 29HU and negative absolute and relative washout. Hormonal exploration indicated that the mass was non-functioning. Magnetic resonance imaging demonstrated close conncections with the inferior vena cava, the portal trunk, the aorta, and the liver. FDG-PET scan showed a mildly hypermetabolic adrenal mass with no other pathological uptake. The pathological study concluded an AG. The patient underwent surgical resection of the mass with a straightforward postoperative course.
Discussion and conclusion: Ganglioneuroma is a benign neuroblastic tumor, with adrenal localization accounting for approximately 21% of cases. The radiological characteristics are nonspecific and can be confused with adrenal cortical carcinoma and pheochromocytoma, thus contraindicating biopsy in this context. It is often sporadic, although associations with ROHHAD syndrome, MEN2A, and Turner syndrome have been reported. Management is based on surgical resection; AG is characterized by close vascular conncetions, which complicates its surgical approach. The prognosis after surgery is favorable, and no adjuvant treatment is required.