Surgical treatment of grave

Nawress Thabet; Omri Malika El; Linda Misbah; Mouna Belakhdher; Jihene Houas; Abir Meherzi; Monia Ghammam; Hamza Elfekih; Wassim Kermani; Mohamed Abdelkafi

doi:10.1530/endoabs.110.EP1445

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Endocrine Abstracts (2025) 110 EP1445 | DOI: 10.1530/endoabs.110.EP1445

ECEESPE2025 ePoster Presentations Thyroid (198 abstracts)

Surgical treatment of grave’s disease in children: a report of five cases

Nawress Thabet ¹ , Malika El Omri ² , Linda Misbah ² , Mouna Belakhdher ² , Jihene Houas ² , Abir Meherzi ² , Monia Ghammam ² , Hamza Elfekih ³ , Wassim Kermani ² & Mohamed Abdelkafi ²

Author affiliations

¹Farhat Hached University Hospital, ENT Department, Sousse, Tunisia; ²Farhat Hached Hospital, Department of ENT and Head and Neck Surgery, Sousse, Tunisia; ³Farhat Hached Hospital, Department of Endocrinology, Sousse, Tunisia.

JOINT680

Objective: To analyze the epidemiological and clinical features of children who underwent thyroid surgery for Grave’s disease at our departmet and to evaluate the indications and outcomes of surgical treatment.

Materials and Methods: This retrospective study includes five pediatric cases of thyroid surgery performed between 2010 and 2022 for Grave’s disease.

Results: The mean age was 16.8 years (10-17 years), and all patients were female. The average time from diagnosis to surgery was 20.3 months. At diagnosis, 60% of patients had multinodular goiters, while 40% had diffuse and homogeneous goiters. Median FT4 and TSH levels were 12.8 pmol/land 0.05 mU/l, respectively. Surgical indications included thyroid nodules (60%, with compression in one case), resistance to medical treatment (20%), and severe ophthalmopathy (20%). Total thyroidectomy was performed in all cases, with no malignancy detected. Postoperative complications were minimal, with only one case of transient hypocalcemia.

Conclusion: Total thyroidectomy is a safe and effective treatment for pediatric Grave’s disease, particularly in cases of treatment resistance or severe manifestations. When performed by experienced surgeons, it provides definitive management with a low risk of complications.