Endocrine Abstracts

JOINT3881

Introduction: Papillary thyroid carcinoma is the most common type of thyroid cancer. Although it is more prevalent in women, its occurrence in men is often associated with a poorer prognosis.

Objective: In this context, we conducted a descreptive study aiming to highlight the clinical and histoprognostic characteristics of papillary carcinoma in men.

Materials and Methods: Our study included all male patients followed in the endocrinology department of Ibn Rochd University Hospital in Casablanca for thyroid carcinoma between 2000 and 2024.

Results: The study population comprised 59 patients, with an average age of 50 years (mean age: 50 ± 14.5 years). The follicular variant of papillary carcinoma was the most frequently observed in 35% of patients. Six percent of the patients presented with poor prognostic variants, primarily the oncocytic variant in two cases. Thyroid carcinoma was associated with other neoplasms in 6% of cases. It was unifocal in 71% of patients. Regarding recurrence risk, 5% were at high risk, and 20% at intermediate risk. Lymph node dissection was performed in 13% of cases, with positive findings in three patients. Vascular emboli were present in 16% of cases, and 11% exhibited thyroid capsule invasion. Radioiodine therapy was indicated for 62% of patients. Two patients had secondary metastases, and three retained residual tumor tissue.

Conclusion: Papillary thyroid carcinoma generally has a favorable prognosis. However, its association with the male sex may be linked to a less reassuring prognosis, with a higher frequency of radioiodine therapy and a risk of residual tumor.