ECEESPE2025 ePoster Presentations Thyroid (198 abstracts)
A vesicular carcinoma of the thyroid on Graves’ disease: a rare association
Nouhaila Essafir 1 , Dounia Talbi 1 , Kenza Lazraq 1 , Chaimae Taleb 1 , Fatima Toulali 1 , Ghizlane Sabbar 1 , Kaouatar Rifai 1 , Hind Iraqi 1 & Mohamed Gharbi 1
1Ibn Sina University Hospital, Endocrinology and Metabolic Diseases, Rabat, Morocco
JOINT156
Thyroid carcinoma coexisting with hyperthyroidism is an uncommon occurrence, as low thyroid-stimulating hormone (TSH) levels can suppress the development and growth of differentiated thyroid carcinoma cells. The majority of nodules in patients with low TSH levels are considered to be benign; however, an increasing number of thyroid carcinoma cases are diagnosed in patients with Graves’ disease, toxic goiter and functioning thyroid adenoma We report the case of a vesicular carcinoma discovered on anatomopathological study of a total thyroidectomy in a patient with Grave’s disease The patient was 60 years old on hemodialysis for hypertensive renal failure. Consulted for a cervical swelling with thyrotoxicosis. The biological assessment showed suppressed TSH, elevated T4 and T3 levels, negative anti-TPO antibodies and elevated TSH receptor antibodies. Cervical ultrasonography revealed a multinodular goiter, the most significant nodule was left inferior polar measuring 31x19 mm classified eutirads3. Fine needle aspiration (FNA) of this nodule was non-contributory The patient received synthetic antithyroid drugs until euthyroidism was obtained, then she underwent a total thyroidectomy. Histology concluded to a vesicular micro carcinoma of the thyroid measuring 8 mm in diameter without vascular emboli. The patient did not receive iodine 131, simple monitoring with L-thyroxine inhibitor treatment were indicated. Hyperthyroidism does not exclude the possibility of associated thyroid cancer. The prevalence of this association varies according to recent series, from 0.2% to 8.3%. The association of Graves’ disease and vesicular carcinoma remains rare.
Volume 110
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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