Endocrine Abstracts

JOINT3905

Introduction: Adrenal masses include a range of pathologies, with benign forms being more common than malignant ones. These masses are sometimes discovered in patients with paroxysmal or resistant arterial hypertension and may represent a potentially treatable cause, accounting for 5 to 10% of secondary elevated blood pressure cases.

Objective: This study aims to highlight the clinical, biological, and morphological characteristics of adrenal tumors diagnosed in patients with elevated blood pressure.

Patients and Methods: Retrospective, descriptive, and analytical study including 46 patients hospitalized for the management of adrenal masses in the Department of Endocrinology, Diabetology, Metabolic Diseases, and Nutrition at CHU Ibn Rochd in Casablanca, over a 5-year period (2019-2024). Statistical analysis was performed using Excel.

Results: The study involved 46 patients with a sex ratio of 0.77. The average age was 45 years. The average duration of high blood pressure was 7 years, with 34% of patients on triple therapy, 36% on dual therapy, and 30% on monotherapy. Blood pressure was only controlled in 21% of cases. Tumors identified included pheochromocytomas in 30% of cases, adrenal adenomas in 22%, and other types of tumors in 48%. Computed tomography (CT) was performed in 32 patients, and MRI in 14, revealing adrenal tumors with an average size of 41 mm. Surgical management was carried out in 40 patients, with tumor resection, and adrenalectomy was performed in 6 patients. The outcome showed remission in 71% of patients, the other 29% having desecalated from triple therapy to bi-tharpy in 18% and monotherapy in 11% of cases.

Conclusion: Adrenal masses are a diverse group, often underdiagnosed, yet they play a significant role in the potential remission of elevated blood pressure