A favorable factors influencing glycemic control in pediatric type 1 diabetes patients

Lee Hae Sang; Shim Young Suk; Cho Min Hyung

doi:10.1530/endoabs.110.EP419

EP419

Prev Next

Section Contents Cite

Endocrine Abstracts (2025) 110 EP419 | DOI: 10.1530/endoabs.110.EP419

ECEESPE2025 ePoster Presentations Diabetes and Insulin (245 abstracts)

A favorable factors influencing glycemic control in pediatric type 1 diabetes patients

Hae Sang Lee ¹ , Young Suk Shim ¹ & Min Hyung Cho ¹

Author affiliations

¹Ajou University Hospital, Suwon, South Korea

JOINT493

Backgrounds: To prevent short-term and long-term complications in pediatric type 1 diabetes patients, optimal glycemic control in essential. However, there is a lack of information about the factors that can predict future blood sugar level control among the patients. Through this article, we aim to investigate predictive factors for optimal blood sugar regulation and identify adverse prognostic factors.

Methods: Retrospective chart analysis was conducted on 92 pediatric and adolescent patients with type 1 diabetes mellitus who visited the Department of Pediatrics at Ajou University Hospital from 2000 to the present. The patients were divided into two groups based on their average HbA1c levels over the past year: the well-controlled group (WC, HbA1c < 7.5) and the poorly controlled group (PC, HbA1c ≥ 7.5). Data collection included all possible factors that may be associated with glycemic control of type 1 diabetes.

Results: Out of the total 92 patients, there were 41 patients in the Well-Controlled (WC) group and 51 patients in the Poorly-Controlled (PC) group, with average HbA1c levels of 6.23 ± 0.41 and 8.62 ± 1.53, respectively. The PC group tended to have a higher current age compared to the WC group (156.85 ± 44.834 vs 175.86 ± 36.718 months, P = 0.035). The HbA1c measured after starting insulin treatment was lower in the WC group (6.587 ± 0.872% vs 7.259 ± 1.242%, P=0.003). When using continuous glucose monitoring(CGM) or insulin pump, the chance of being in the PC group was lower (CGM: Odds ratio 0.396, P = 0.036; Insulin Pump: Odds ratio 0.197, P = 0.009). No significant differences in sex, BMI, diabetes duration, initial HbA1c and C-peptide level, and DKA history were noted between WC and PC groups.

Conclusions: Older age and higher HbA1c levels after starting treatment suggest a higher likelihood of poor blood sugar control, requiring intensified care. Furthermore, since the use of CGM and insulin pumps aids in blood glucose control, we should encourage patients to use these.