ECEESPE2025 ePoster Presentations Diabetes and Insulin (245 abstracts)
Hyperuricemia: is it a cardiovascular risk factor?
Siwar Saoudi 1 , Ramla Mizouri 2 , Rym Ben Othman 2 , Hadhemi Belhassen 2 , Faten Mahjoub 3 , Berriche Olfa 4 , Nadia Ben Amor 5 & Jamoussi Henda 4
1Institute of Nutrition of Tunis, Tunis, Tunisia; 2Institute of Nutrition, Tunis, Tunisia; 3Institute of Nutrition, Tunis, Tunisia; 4Institute of Nutrition, Tunis, Tunisia; 5National Institute of Nutrition, Tunis, Tunisia
JOINT3467
Introduction: Hyperuricemia is common in diabetic subjects, especially type 2, particularly in obese patients. Our aim was to investigate the prevalence and risk factors of hyperuricemia in diabetics subjects.
Methods: It was a descriptive cross sectional study conducted in department A of the institute of Nutrition of Tunis which included patients with type 2 diabetes. Hyperuricemia was defined by a uric acid level that exceed 360mg/l.
Results: The total number of patients who participated in the study was 112. The characteristics of the patients were respectively: age 49±9.8 years, Body mass index (BMI) 31± 3.7Kg/m2, HbA1c 9.8±1.57%. The mean waist circumference was 119.1 ± 18.5 cm. The mean duration of diabetic patients was 9±7 years. Hyperuricemia was present in 32.8%, with a mean level of 408 ± 22.6mg/l. A history of stroke, coronary artery disease and arteriopathy were found respectively in 12.4%,14.5% and 34% of cases. Also 75% of subjects presented microangiopathic complications, with 43% having a diabetic neuropathy, 26% with diabetic nephropathy. As for the metabolic profile, 98.1% with low HDLc, high LDLc in 59.7%, high triglycerides in 76.4 %. Hyperuricemia was positively correlated with BMI (p =0.007), waist circumference (p =0.01) and duration of diabetes (p = 0.009). Hyperuricemia was significantly more frequent with diabetic nephropathy (p = 0.031) and with dyslipidemic patients (p =0.001). Thus, 89% of patients met the International Diabetes Federation definition of metabolic syndrome.
Conclusion: In conclusion, Hyperuricemia was common in our study. It was positively correlated with BMI, waist circumference, length of diabetes, diabetic nephropathy and dyslipidemia, making it a cardiovascular risk factor.
Volume 110
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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