ECEESPE2025 ePoster Presentations Adrenal and Cardiovascular Endocrinology (170 abstracts)
How to discover non-functioning adrenal cortical adenomas
Yesmine Elloumi 1 , Mouna Elleuch 1 , Yasmine Abdelkafi 1 , Nada Hassairi 1 , Kouloud Boujelben 1 , Hadjkacem Faten 1 , Nadia Charfi 1 , Mouna Mnif 1 , Mohamed Abid 1 , Dhoha Ben Salah 1 & Nabila Rekik Majdoub 1
1Hedi Chaker University Hospital, Endocrinology Department, Sfax, Tunisia
JOINT1365
Background: Non-functioning adrenal cortical adenomas (NFAA) represent 70-90% of non-functioning adrenal incidentalomas. Despite being non-secretory, these tumors may exhibit minimal, inapparent, yet prolonged cortisol secretion, which can predispose individuals to components of the metabolic syndrome. This underscores the importance of screening for NFAA and the need for continuous monitoring to ensure optimal management and early detection of potential metabolic complications.
Methods: The study was retrospective and included patients followed for non-functioning adrenal cortical adenomas associated with metabolic disorders. These patients were enrolled from the Endocrinology-Diabetology Department of Hedi-Chaker University Hospital in Sfax.
Results: Our cohort consisted of 31 patients with non-functioning adrenal cortical adenomas, aged between 34 and 80 years. A female predominance was observed in 60% of cases. The adrenal adenomas were diagnosed incidentally in 90.6% of patients, with a hypertensive peak in 6%, and refractory hypertension as the reason for diagnosis in 3%. Features such as truncal obesity, with or without hypertension, facial erythema, rapid weight gain, melanoderma, and hypokalemia were not identified as presenting symptoms. Abdominal ultrasound was performed for an unrelated indication and incidentally led to the discovery of an adrenal incidentaloma in 58% of the sample.
Conclusion: Early detection of NFAA through screening and continuous follow-up is essential for optimizing patient management and preventing long-term complications.
Volume 110
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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