Endocrine Abstracts

JOINT2319

Introduction: Diabetic pregnancy is a high-risk pregnancy requiring optimal programming and glycemic balance to avoid maternal-fetal complications.

Objective: To assess factors influencing glycemic balance in pregnant diabetic women.

Materials and methods: This is a retrospective study over a 2-year period conducted at the Endocrinology, Diabetology, Metabolic Diseases and Nutrition Department of the Hassan II University Hospital in Fez. We included all pregnant patients with pre-existing diabetes who agreed to participate. Patients with gestational diabetes were excluded. Glycemic balance was judged by an HbA1c <6.5% and a glycemic cycle within the target in >90% (glycemic targets in preprandial between 0.60 and 0.95 and in postprandial <1.2 g/l) Eating habits were assessed by a food diary Statistical analysis was performed using SPSS 26 software. We retained the value P<0.05 as the significance threshold.

Results: We collected 80 patients, the average age was 35.56 ± 5.4 years, 27% had type 1 diabetes and 73% type 2 diabetes, the average duration of diabetes was 8.7 ± 3.1 years. Only 9.2% planned the pregnancy. 61.2% had a hbA1c < 6.5%. 89% of patients ate 3 meals per day and 58% ate one to two snacks per day. 56% abused slow sugars and 44% consumed fast sugars. Mean HbA1c was significantly higher in T1D than T2D (P<0.001), in patients who had not planned their pregnancies (P = 0.02), in patients who made dietary errors (P<0.01), and in patients with a long duration of diabetes (0.01)

Conclusion: Our study highlights several factors impacting glycemic balance in diabetic women, particularly in pregnant type 1 diabetic women, with a long duration of diabetes development. Hence the interest in education on programming and optimal balance of diabetes in preconception ]