Endocrine Abstracts

Global encephalopathy is a rare complication of Hashimoto’s thyroiditis. It typically presents with seizures, ataxia and tremors and responds to steroid therapy. Limbic encephalitis (LE) is even less well described in paediatric population. It presents with medio-temporal lobe symptoms (memory impairment, temporal lobe seizures and disturbances of affect) caused by inflammation within the hippocampus, amygdala, hypothalamus, insular and cingulate cortex. LE most commonly ...

Case history: A 26-year-old female presented with acute left-sided loin pain. There was a preceding dull ache for two months. She had no dysuria or haematuria. Her past medical history was unremarkable except for rhinosinusitis. Investigations: Abdominal CT revealed oval shaped lesion adjacent to the upper pole of the left kidney. The left adrenal gland could not be separately visualized. The lesion had mass effect on the fundus of the stomach. Adrenal M...

Introduction: Whilst effective, targeted checkpoint inhibitor monoclonal antibodies are associated with immune-related adverse events including endocrinopathies. Increased licensed oncological indications for these agents raise the need for effective screening, monitoring and ongoing treatment of endocrinopathies. The aim of our study was to investigate potential predictive factors that may identify patients at risk of endocrinopathies....

Introduction: Whilst effective, targeted checkpoint inhibitor monoclonal antibodies are associated with immune-related adverse events including endocrinopathies. Increased licensed oncological indications for these agents raise the need for effective screening, monitoring and ongoing treatment of endocrinopathies. The aim of our study was to investigate potential predictive factors that may identify patients at risk of endocrinopathies....

A secondary hypertension service was set up by the Endocrinology team in 2016 aiming to capture young hypertensive (age <30 years), refractory hypertension and hypertensive emergency to provide holistic care. A pathway was developed streaming Hypertensive emergencies to the high dependency area for intravenous treatment and hypertensive urgencies to the Ambulatory care for oral medications. All patients were linked to a secondary hypertension clinic. Staring with one clini...

Thyroid hormones play an important roles during pregnancy and lactation. During pregnancy the foetus depends entirely on the dam for the supply of nutrients and after parturition for the formation of colostrum. To meet out these needs the dam attempts to reset up its endocrine function including thyroid gland. There is also a change in body metabolic rate and some of the related biochemical components which are mainly controlled by thyroid hormones. Therefore an experiment was...

Case: A 36-year-old gentleman presented with two month history of severe headaches, vomiting, polyuria and polydipsia. He reported profound episodic sweating especially on exertion and gradual weight loss. He was hypertensive (220/110 mmHg) at presentation. He had no palpitations, anxiety, dizziness, flushing or pallor. He had no diarrhoea or abdominal pain. His only family history was of Type 2 diabetes mellitus.Investigation: Biochemical investigations...

Introduction: COVID 19 is now a global pandemic. Diabetes is postulated to be a risk factor for mortality due to COVID –19Methods: We retrospectively evaluated the inpatient medical record data, of patients admitted over last two months in a public hospital in Central India to compare the attributes of mortality in patients without T2DM and with T2DM including their glycemic clinical characteristics. Unpaired t – test and Fisher’s exact...

Background: Hyponatremia is the most common electrolyte disorder encountered in clinical practice. Vulnerable cohorts tend to be hospitalised patients where it tends to occur in 15-20% of the patients and the other category being nursing home residents. Significant risk factors are increasing age, and polypharmacy.Aims: We aimed to look at the management of hyponatremia at our hospital, check adherence with the trust gui...