Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep125 | Calcium and Bone | ECE2023

Application of untargeted metabolomics in primary hyperparathyroidism

Wielogorska-Partyka Marta , Podgorska Beata , Mocarska Karolina , Godzień Joanna , Siemińska Julia , Ciborowski Michał , Kozłowska Gabriela , Szelachowska Małgorzata , Adamska Agnieszka , Popławska-Kita Anna , Dzieciol Janusz , Krętowski Adam , Siewko Katarzyna

Background: The excessive secretion of parathormone by parathyroid glands is a common disorder known as hyperparathyroidism. With a prevalence of 0.1-0.4 percent in the general population and 2-4 percent in post-menopausal women, primary hyperparathyroidism is the third most frequently reported endocrine disorder. According to estimates, the prevalence of primary hyperparathyroidism has escalated in recent years, probably due to the increasing rate of parathormone and calcium ...

ea0035p776 | Obesity | ECE2014

Application of LC–MS and CE–MS based metabolomics to study type 2 diabetes development in lean, overweight and obese humans

Ciborowski Michal , Kretowski Adam , Adamska Edyta , Citko Anna , Waszczeniuk Magdalena , Wilk Juliusz , Golonko Anna , Pliszka Justyna , Lipinska Danuta , Goscik Joanna , Rusak Magdalena , Godzien Joanna , Barbas Coral , Gorska Maria

The risk of type 2 diabetes mellitus (T2DM) development is related to BMI, therefore this disease mainly occurs among overweight (OW) and obese (OB) people. However lean (L) individuals may also suffer from T2DM. The evolution of T2DM is a multistep process and starts with insulin resistance (IR), which may evolve into pre-diabetic state i.e.: impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT). In up to 70% of patients pre-diabetic state evolves into T2DM. ...