Searchable abstracts of presentations at key conferences in endocrinology

ea0043oc9 | Cardiovascular Outcome Studies | WCTD2016

Years of Life Gained by Multifactorial Intervention in Patients with Type 2 Diabetes and Microalbuminuria – 21 Years Follow-Up on the Steno-2 Study

Ollgaard Jens , Gaede Peter , Carstensen Bendix , Rossing Peter , Lund-Andersen Henrik , Parving Hans-Henrik , Pedersen Oluf

Aims: To study the potential long-term impact of a 7.8 years intensified, multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria in terms of gained years of life and years free from incident cardiovascular disease.Methods: The original intervention (mean treatment duration 7.8 years) involved 160 patients with type 2 diabetes and microalbuminuria that were randomly assigned to either conventional therapy or intensified...

ea0028pl4biog | Society for Endocrinology European Medal Lecture | SFEBES2012

Society for Endocrinology European Medal Lecture

Juul Jens

Jens Juul, Holst, Professor of Medical Physiology, University of Copenhagen, Copenhagen, Denmark AbstractJens Holst, is a Professor of Medical Physiology at the University of Copenhagen in Denmark. He is also the Vice Chairman of the board of the Department of Biomedical Sciences at the University of Copenhagen, Chairman of the Faculty's Research Center for Diabetes and Obesity and Director at Marie Krogh Center for M...

ea0009s2biog | Clinical Endocrinology Trust Visiting Professor Lecture | BES2005

Clinical Endocrinology Trust Visiting Professor Lecture

Jens Sandahl Christiansen

Jens Sandahl Christiansen, Medical Department M, Aarhus University Hospital, Aarhus, Denmark AbstractJens Sandahl Christiansen, MD, is professor of medicine and consultant endocrinologist at Aarhus University Hospital, Kommunehospitalet, Aarhus, Denmark. He graduated from Copenhagen University Medical School, and has been trained in diabetes and endocrinology in Copenhagen and Aarhus.Dr. Chr...

ea0049s9.1 | Novel type 2 diabetes treatment: Beyond glycaemic control | ECE2017

Experimental models

Holst Jens

One of the most surprising and inspiring experimental models for type 2 diabetes therapy is gastric bypass surgery. Recent 5-year results have demonstrated massive improvements in glycaemic control and body weight, lipids and quality of life after surgery compared to intensive medical therapy (the Stampede trial). Therefore, it is imperative to identify the responsible factors with a view to utilize this knowledge for future therapy without surgery. Substantial evidence sugges...

ea0049mte2 | (1) | ECE2017

Diagnosis and management of GH deficiency - from childhood to adulthood

Jorgensen Jens

Pituitary dwarfism has been known for many decades, originally as a component of organic panhypopituitarism. GH for clinical use was purified by Maurice Raben from human cadaveric pituitaries and tested for the first time and with success in 1957 in a patient with childhood onset disease. Moreover, pivotal short term studies on the metabolic effects were performed in both healthy and hypopituitary adults. The concomitant introduction of imunnoassays for GH led to the introduct...

ea0037ew1.2 | Practical publishing advice | ECE2015

The peer review process

Mittag Jens

The peer review process is a critical step in whether a manuscript will be accepted for publication. In this talk we will present the editorial processes that happen behind the scenes under the label ‘under review’, how reviewers are selected, how authors can facilitate the peer review process, and how recent attempts have tried to undermine the classic peer review system....

ea0026mte19 | (1) | ECE2011

Management of primary hyperparathyroidism

Bollerslev Jens

The clinical presentation of primary hyperparathyroidism (PHPT) has changed dramatically after increased accessibility to biochemical auto-analysers and the diagnosis is today often made by change in patients without specific symptoms. Operative treatment is recommended in patient with markedly increased calcium levels or typical symptoms. However, the vast majority of patients in the modern clinic do not present organ related symptoms and their calcium levels are only slightl...

ea0022s12.4 | Thyroid hormone metabolism and action: new developments | ECE2010

Significance of thyroid hormone receptor α in metabolism

Mittag Jens

Thyroid hormone (TH) is long known for its profound effects on metabolism. Novel studies have revealed that these effects are not restricted to the cellular and organ level, and that TH also affects metabolism by altering the autonomic nervous system via TH receptor α1. Mice expressing a mutant R384C TH receptor α1 display a central sympathetic hyperactivation of their brown adipose tissue, which causes severe hypermetabolism and resistance to high-fat diet-induced o...

ea0020s13.2 | Pro & con – Surgery for ‘asymptomatic’ hyperparathyroidism | ECE2009

Management of mild primary hyperparathyroidism

Bollerslev Jens

The clinical presentation of primary hyperparathyroidism has changed dramatically after increased accessibility to biochemical auto-analysers and the diagnosis is today often made by change in patients without specific symptoms. Operative treatment is recommended in patient with markedly increased calcium levels or typical symptoms. However, the vast majority of patients in the modern clinic do not present organ related symptoms and their calcium levels are only slightly incre...

ea0016pl8 | Central regulation of appetite and body weight – the role of peripheral signals | ECE2008

Central regulation of appetite and body weight: the role of peripheral signals

Bruning Jens

The ever-growing obesity epidemic puts an enormous burden on our societies. The need for the development of novel therapeutic interventions necessitates the exact understanding of the underlying regulatory principles in energy homeostasis. Over the last 10 years, the hormonal and nutritional factors communicating the energy state of the body to the central nervous system to adapt caloric intake and energy expenditure have rapidly extended our understanding on the mechanisms co...