Abstract Search

Loss of beta cell mass in the pancreas characterises type 1 and late-stage type 2 diabetes, resulting in a reduction of insulin levels. The pancreas has a very limited regenerative potential during homeostasis. Despite its quiescent nature, recent in vivo models suggest that a certain degree of regeneration and cellular interconversion is possible in the adult pancreas. The molecular regulation of this plasticity shares remarkable similarities with pancreas beta cell different...

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ea0077bpw2.2 | Model systems | SFEBES2021

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ea0077bpw2.3 | Model systems | SFEBES2021

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ea0077hdi1.1 | How do I. . .? 1 | SFEBES2021

Dr Claire Higham

Higham Claire

This talk will cover the currently available evidence describing the endocrine and metabolic consequences of radiotherapy treatment to the hypothalamus and pituitary. A practical approach to surveillance, diagnosis and management of these consequences in childhood and adult cancer survivors will be provided....

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ea0077hdi1.2 | How do I. . .? 1 | SFEBES2021

How do I investigate a young person with a low trauma fracture?

Walsh Jennifer

Long bone fractures are quite common in teenagers during rapid growth, due to the lag between longitudinal growth and cortical consolidation and trabecular structure. Vertebral fractures are uncommon in young people, and should always raise concern. A low trauma fracture is defined as a fall from standing height or less, but it is important to take a good history of the mechanism of fracture, and any previous fractures. Family history is important too....

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Endocrine Abstracts

Modelling diabetes using iPSCs and adult derived organoids

Dr Claire Higham

How do I investigate a young person with a low trauma fracture?

BiosciAbstracts