Searchable abstracts of presentations at key conferences in endocrinology

ea0014p40 | (1) | ECE2007

PED levels are increased in peripheral blood leucocytes from euglycaemic subjects at-risk of type 2 diabetes

Valentino Rossella , Lupoli Gelsy Arianna , Formisano Pietro , Esposito Iolanda , Alberobello Anna Teresa , Perfetti Anna , Cirillo Michele , Gennarelli Nicola , Gargiulo Giovanna , Lobello Roberto , Beguinot Francesco

Background: Phosphoprotein enriched in diabetes (PED) is a scaffold protein widely produced in different tissues; it is involved in multiple cellular functions, including insulin-regulated glucose transport. Previous findings showed that in individuals with type 2 diabetes (T2D) the PED gene is overexpressed in skeletal muscle (SM) and adipose tissue (AT), both target tissues for insulin activity. Our group has recently evidenced that PED protein is also expressed in periphera...