ea0073aep384 | Endocrine-Related Cancer | ECE2021
Berbel Inmaculada
, Alors-Perez Emilia
, Juan M Jiménez-Vacas
, Ricardo Blázquez-Encinas
, Cristina Viyuela-García
, Álvaro Arjona-Sanchez
, Juan Manuel Sánchez-Hidalgo
, Marina Sánchez-Frías
, Enrique Gómez-Gómez
, Ortiz Manuel Gahete
, Alejandro Ibañez Costa
, Luque Raul M.
, Justo P. Castaño
IntroductionAlternative splicing allows the generation of multiple RNA isoforms from a single pre-RNA molecule, and thereby contributes to a multitude of physiological processes, but can also be involved in many diseases, including cancer. Indeed, disruption of alternative splicing has been linked to key cancer features, such as tumor growth, metastasis and hormone responsiveness and is increasingly regarded as a novel and transversal cancer hallmark. Th...