Endocrine Abstracts

Introduction: 25 314 children and young people <18 years with diabetes in England and Wales have been looked after in 178 paediatric diabetic units (PDUs) across the country. In 2012–2013, BPT has been introduced with 13 mandatory requested criteria, one of them is; each patient should have an annual assessment as to whether input to their care by a clinical psychology input is needed, and access to psychological support as appropriate. Therefore we aimed to study the...

Introduction: Continuous s.c. insulin infusion delivered via insulin pump has enabled patients with diabetes mellitus type 1 to improve metabolic control and lead healthier lives1. However some patients are experiencing problems with their pumps.Aim and methods: A service review was carried out to look at the incidence of pump related problems using an online questionnaire survey.Results: The response rate was 85% for th...

Introduction: The study aimed to review the service provided for children and young people with type 1 diabetes mellitus focusing on their quality of life (QoL) before and after commencing insulin pump therapy.Methods: An online survey using survey monkey was carried out. Each questionnaire had 10 questions and it was filled by either patients or their parents based on the age group.Results: Forty-two patients are currently on insu...

Introduction: Van Wyk-Grumbach syndrome was first described in 1960 in patients presenting with long standing juvenile hypothyroidism, delayed bone age and precocious puberty. Literature review indicates only few cases reported in males compared to females. We are reporting this case in a male patient who presented with short stature.Case: A 7.25-year-old boy was referred for endocrine opinion due to short stature. He had not grown over the last 18 month...

Introduction: Bedside blood ketone measurement has often been used in the management of diabetic ketoacidosis. However there is no available data on its reliability in the evaluation of hypoglycaemia in children. We aimed to assess the reliability of bedside ketones (beta-hydroxybutyrate (BHB)) in the evaluation of hypoglycaemia in children.Methods: We collected data on 20 children who had paired measurement of bedside and lab BHB at the end of a control...

Introduction: Congenital hyperinsulinism (CHI) is a rare genetic disorder that is characterised by persistent hypoglycaemia in infants and children. We are reporting a rare case of diffuse CHI who was also found to have hypopituitarism and several other congenital anomalies. A similar association has not been reported in literature.Case: A female baby was born at 42 weeks gestation with a birth weight of 4.185 kg (1.72 SDS). She suffered shoulder dystoci...

Introduction: We do not fully understand why some hypothyroid patients complain of persistent symptoms despite normalisation of TSH with levothyroxine therapy. Recent evidence in adults suggests that polymorphism in deiodinase2 enzyme could lead to lower level of T3 in some tissues and persistence of symptoms. A combination therapy with T3/T4 may improve symptoms especially psychological well-being, mood and memory in such patients. Combination...

Case report: A 13-year-old male presented with a 10-day history of vomiting. He was haemodynamically stable. His biochemistry was evaluated revealing a sodium level of 96 mmol/l. He had been seen 2 years previously with short stature. Sodium was normal at this time. He had speech and language delay, learning difficulties and was under investigation for autism. He had reportedly salt craved for years. Potassium, urea, creatinine, and glucose were normal throughout the admission...

Background: Disorders of sexual development (DSD) are estimated to occur in every 1 in 4500 births. This project builds upon previous work by the authors to explore the knowledge and management of paediatric junior doctors in a single deanery. The majority of junior doctors stated that they would seek the advice and explanation of paediatric consultant. We therefore attempted to qualify the knowledge and management strategies of the region-wide consultant body with regards to ...

Introduction: Recently, the factory calibrated FreeStyle Libre (FSL) flash glucose monitoring system has been introduced for use in patients with diabetes mellitus. We assessed the accuracy of FSL compared to the finger prick capillary blood glucose (CBG) over a 2 week period in patients with congenital hyperinsulinism (CHI) and assessed the parents’ experience of using FSL.Methods: About 346 episodes of CBG along with corresponding swipe FSL readin...