Searchable abstracts of presentations at key conferences in endocrinology

ea0093oc11 | Oral communication 2: Neuroendocrinology | EYES2023

Soluble alpha klotho, a new biomarker of growth hormone action

Schweizer Junia Ribeiro de Oliveira Longo , Schilbach Katharina , Gagliardo Anica Pauline , Haenelt Michael , Peters Annette , Thorand Barbara , Bidlingmaier Martin

Background: Soluble alpha klotho (sαKL) is high in active acromegaly, normalizes after disease control, and therefore is suggested as a new biomarker for growth hormone (GH) excess. However, little is known about the impact of biological variables other than GH.Methods: Serum sαKL (pg/ml) was measured by ELISA (IBL, Hamburg, Germany). We first evaluated pre-analytical stability, defined a reference interval for sαKL in healthy subjects (A:...