ea0035p957 | Steroid metabolism and action | ECE2014
Michetti Grazia
, Trementino Laura
, Marcelli Giorgia
, Apolloni Gloria
, Taruscia Domenica
, Frasca Giovanni Maria
, Boscaro Marco
, Faloia Emanuela
, Arnaldi Giorgio
Introduction: New onset diabetes after transplantation (NODAT) is a recognized metabolic complication of kidney transplantation: its rates at 12 months after transplantation is between 20 and 50% for kidney recipients and it is associated with increased risks of graft rejection, infection, cardiovascular disease and death. Transplant-specific risk factors for NODAT,such as corticosteroids and calcineurin inhibitors, play a dominant role in its pathogenesis. Furthermore polymor...