ea0029p1106 | Neuroendocrinology | ICEECE2012
Apostolatos A.
, Cooper D.
, Patel N.
Older population and people with type II diabetes have a significantly higher rate of decline in cognitive function. However, the mechanisms are poorly understood. There are strong links between insulin and cognitive function supported by epidemiological data from humans and animal studies and in vitro research. Protein kinase C (PKC) signaling cascades and insulin pathways are closely integrated. The consequences of PKC activation by insulin in the CNS influence memory...