Endocrine Abstracts

Among its numerous comorbidities, obesity is often linked to central hypogonadism in men, i.e., low circulating levels of gonadotropins and testosterone. While this condition of obesity-induced hypogonadism (OIH) is frequently neglected, it has been suggested to contribute to the metabolic complications of male obesity. However, the mechanisms of OIH, and even its actual role in the metabolic alterations of obesity remain ill defined. Our recent data suggest that OIH is bound ...