ea0029p1196 | Obesity | ICEECE2012
Balaz M.
, Ukropcova B.
, Kurdiova T.
, Penesova A.
, Skyba P.
, Vlcek M.
, Belan V.
, Klimes I.
, Payer J.
, Imrich R.
, Smith S.
, Tkacova R.
, Gasperikova D.
, Ukropec J.
Adult GH deficiency (GHD) is associated with prediabetes and low levels of GH are found in obesity. We hypothesized that zinc-α2-glycoprotein (ZAG), a novel adipokine reduced in obesity, is regulated by GH. ZAG serum and adipose tissue expression were measured in three study populations: i) cachectic (BMI=19.3±0.5 kg/m2), lean/overweight (BMI=26.0±0.5 kg/m2) and obese (BMI=36.0±1.6 kg/m2) patients with chronic obstructive pu...