Searchable abstracts of presentations at key conferences in endocrinology

ea0014oc1.5 | Thyroid clinical | ECE2007

CTLA- 4 gene polymorphisms and autoimmune thyroid diseases: meta-analyses of published and individual-level data

Kavvoura Fotini , Akamizu Takashi , Awata Takuya , Ban Yoshiyuki , Chistiakov Dimitry , Frydecka Irena , Ghaderi Abbas , Gough Stephen , Hiromatsu Yuji , Ploski Rafal , Wang Pei-Wen , Ban Yoshio , Bednarczuk Tomasz , Chistiakova Emma , Chojm Marcin , Heward Joanne , Hiratani Hitomi , Juo Suh-Hang Hank , Karabon Lidia , Katayama Shigehiro , Kurihara Susumu , Liu Rue-Tsuan , Miyake Ikuyo , Omrani Gholam-Hossein , Pawlak Edyta , Taniyama Matsuo , Tozaki Teruaki , Ioannidis John PA

Background: CTLA-4 polymorphisms have been widely examined for their associations with autoimmune thyroid diseases (Graves’ disease [GD] and Hashimoto thyroiditis [HT]) but their relative population effect remains unclear.Methodology/Principal findings: Meta-analyses of group-level data from 32 (n=11.019 subjects) and 12 (n=4.479) published and unpublished studies were performed for the association of the A49G polymorphism with ...