Searchable abstracts of presentations at key conferences in endocrinology

ea0065p226 | Metabolism and Obesity | SFEBES2019

Are PCSK9 inhibitors delivering as promised?

Bashir Bilal , Bharaj Harnovdeep , Hutchesson Andrew , Banerjee Moulinath

Background and aims: Statins has long been used as first line treatment option for hypercholesterolemia however; half of population doesnÂ’t achieve target LDL reduction. Proprotein convertase subtilisin kexin 9 inhibitors (PCSK9i) are a promising addition to anti-dyslipidemic armamentarium. Aim of this study is to find out the efficacy of PCSK9 inhibitors in a district general hospital of Northwest of England.Method: We identified all the patient wh...

ea0065p380 | Reproductive Endocrinology and Biology | SFEBES2019

Seeing is believing – is that always true?

Bashir Bilal , Das Sangeeta , Yeung George , Razzaq Rubeena , Pearson Mark , Shepherd Laura , Banerjee Moulinath

Introduction: Hirsutism affects 10% of the female population caused by hyperandrogenism of benign aetiologies or androgen-secreting tumours. Tumorous causes of hyperandrogenism include androgen producing ovarian or adrenal tumours. Leydig cell tumours are rare ovarian testosterone producing tumours that comprise 0.1% of total ovarian tumours. It is rare in postmenopausal women and present with features of hyperandrogenaemia or hyperestrogenemia.Case: We ...

ea0070aep657 | Pituitary and Neuroendocrinology | ECE2020

The impact of variations in laboratory measurements of IGF-1 and random growth hormone on the classification of acromegaly disease activity status: Lessons from the UK Acromegaly Register Reference Laboratory

Bashir Bilal , Adam Safwaan , Monaghan Philip , Plummer Zoe , Archer Natasha , Ayuk John , Trainer Peter

Background: The UK Acromegaly Register contains data for 2700 patients. IGF-1 and random growth hormone (GH) measurements are used for disease monitoring. The registry reference laboratory (RRL) uses the Immunodiagnostic systems (IDS)-iSYS immunoassay platform for GH and IGF-1. The RRL uses age- and sex-specific reference ranges for IGF-1. We compared IGF-1 and GH results fromlocal laboratories to those of the RRL (pre-defined as the Gold standard) to determine the extent of d...