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ea0041gp186 | Reproduction & Endocrine Disruption | ECE2016

FSH increases the different LH- and hCG-dependent intracellular signalling and the downstream life/death signals in vitro

Casarini Livio , Riccetti Laura , De Pascali Francesco , Nicoli Alessia , Tagliavini Simonetta , Trenti Tommaso , Battista La Sala Giovanni , Simoni Manuela

Background: Luteinizing hormone (LH) and choriogonadotropin (hCG) are glycoprotein hormones regulating ovarian function and pregnancy. They were routinely used in assisted reproduction techniques (ART) assuming they are equivalent, due to their binding to a common receptor (LHCGR). However, differences between LH and hCG were demonstrated at molecular and physiological level.Aim: The aim of this study is to evaluate how follicle-stimulating hormone (FSH)...

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FSH increases the different LH- and hCG-dependent intracellular signalling and the downstream life/death signals in vitro

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