ea0014p129 | (1) | ECE2007
Dardano Angela
, Falzoni Simonetta
, Polini Antonio
, Bemi Alessia
, Solini Anna
, Caraccio Nadia
, Di Virgilio Francesco
, Monzani Fabio
Extracellular nucleotides, via specific plasma membrane receptors (P2Rs) of the X and Y subtype, modulate several cell functions, including cell-to-cell cross talk. We have previously demonstrated the expression of several functional P2XRs subtypes, including P2X7, in primary human thyrocytes. P2X7 is the main player in inflammation and immunomodulation; a strong expression of this receptor has been shown in several human solid tumors. Polymorphisms of the gene enco...