Endocrine Abstracts

A 36 year old gentleman with a BMI of 22 was seen in diabetes clinic. He had a 1 year history of type 2 diabetes (and no family history of diabetes). He was on insulin but had later been started on metformin and had been able to reduce his insulin dose. He was advised to continue reducing his insulin dose and the consultant decided that due to the patient’s morphology he would request an IGF-1 level. At his next follow up the patent had vastly reduced his insulin doses an...

A 42 year old gentleman was referred to endocrinology clinic by a consultant urologist due to an incidental finding of a 14 mm adrenal nodule on the patient’s right adrenal gland. He was originally seen by gastroenterology having been referred due his 7 year history of twice yearly attacks lasting around 30 min, comprising of flushing of the face, palpitations, burning sensation in his stomach, sweating, vomiting and loose bowel motions. The gastroenterology consultant di...

The pharmaceutical industry provides challenging and rewarding career opportunities for physicians. Given that clinical drug development for cardio-metabolic and oncological indications are the focus for many pharmaceutical companies, physicians and scientists with specialist training in endocrinology, diabetes and metabolism are in demand. In addition to responsibilities in clinical trial design, drug safety and regulatory affairs, physician scientists with an intimate knowle...

The pharmaceutical industry provides challenging and rewarding career opportunities for physicians. Given that clinical drug development for cardio-metabolic and oncological indications are the focus for many pharmaceutical companies, physicians and scientists with specialist training in endocrinology, diabetes and metabolism are in demand. In addition to responsibilities in clinical trial design, drug safety and regulatory affairs, physician scientists with an intimate knowle...

Mr JP, a 64-year-old gentleman with a background of type 2 diabetes mellitius, ischaemic heart disease and hypertension was referred due to hypercalcaemia. He had a long history of hypercalcaemia, 9 years according to the biochemistry records and his adjusted calcium was 2.9 mmol/l on presentation. His parathyroid hormone level was 8.1 pmol/l. JP had clear symptoms of hypercalcaemia – polydipsia, polyuria, problems with concentration, fatigue, headaches and generalised ac...

Abstract unavailable at the time of publishing...

Temozolomide (TMZ) is an oral chemotherapy first used for pituitary tumours in 2006. Over the past 12 years experience and confidence using this treatment has increased. Temozolomide is effective: with about 50% of cases showing a tumour response. This figure rises to 70% if stable disease is regarded as a tumour response. The effectiveness appears to be similar in both aggressive adenoma and carcinoma. Functioning tumours show a better response as compared with non-functionin...

A 51F domestic worker presented with classic clinical and biochemical features of acromegaly. This included a long history of arthralgia, increase in hand and foot size, paraesthesia requiring bilateral carpal tunnel release and coarsening of facial features. She was also newly diagnosed with hypertension and diabetes. On examination she demonstrated central adiposity, a prominent supra orbital ridge and nasal bridge, prognathism, interdental spacing, skin tags, and broad hand...

Introduction: Primary hyperparathyroidism and vitamin D deficiency are two common conditions. Their coexistence also seems frequent and could aggravate clinical and biological manifestations of primary hyperparathyroidism. The aim of this work is to analyze the clinical and paraclinical parameters of this disease according to vitamin D status.Methods: Retrospective study conducted at the Department of Endocrinology Diabetology and Metabolic Diseases of t...

Introduction: Primary hyperparathyroidism is associated with an increased prevalence of high blood pressure. The objective of our work was to evaluate the prevalence and blood pressure profile in patients with primary hyperparathyroidism.Methods: Retrospective study conducted at the Department of Endocrinology Diabetology and Metabolic Diseases of the University Hospital of Casablanca for a period of 4 years (2014–2018) including all patients follow...