Endocrine Abstracts

A 22 year old man was referred to the endocrine unit at St Barts following an abnormal visual field test with his optician and subsequently with ophthalmology at Moorfields eye hospital. At presentation he was noted to be very tall (194 cm), with facial features of growth hormone excess. Despite starting puberty at the age of 12–13 he had experienced continued vertical growth - he was the tallest in his family and his parents had commented that he was continuing to grow, ...

A 35 year old lady presented to endocrine services with a background of attempted conception and oligomenorrhoea. Presenting features were typical of acromegaly including sweating, acne and median nerve entrapment. Growth hormone day curve showed unrelenting high levels of growth hormone. Serum IGF-1 was elevated at 154 nmol/l (normal 14.2–36.9). Other pituitary blood tests were within normal limits. A pituitary macroadenoma measuring 1.5×1.5×1.3 cm was found on...

A 36 year old gentleman with a BMI of 22 was seen in diabetes clinic. He had a 1 year history of type 2 diabetes (and no family history of diabetes). He was on insulin but had later been started on metformin and had been able to reduce his insulin dose. He was advised to continue reducing his insulin dose and the consultant decided that due to the patient’s morphology he would request an IGF-1 level. At his next follow up the patent had vastly reduced his insulin doses an...