Endocrine Abstracts

Background: Toxic thyroid nodules are difficult to manage medically. Surgical versus radioiodine therapy can be chosen in light of risk and benefit for individual cases.Clinical case: 72 years old woman presented with 3 months history of hands tremor. There was no associated palpitations, weight loss, sweating, diarrhoea or mood change. She reported mild tiredness. She had never noticed any lump or pain in her neck. There was history of cold intolerance ...

68 years old female initially referred to endocrine clinic in November 2016 for assessment of fluctuating thyroid function. She had a history of long standing primary hypothyroidism, stable on treatment with 100 mcg Levothyroxine. In last one year, Levothyroxine was tapered and stopped due to persistent suppression of TSH and high normal Free T4. Last tests showed TSH of <0.01mIU/l and Free T4 of 27.1 pmol/l. She had ongoing complaints of feeling increasingly tired and gen...

Grave’s disease is an autoimmune mediated thyrotoxicosis which accounts for 50–80% of cases of hyperthyroidism. In addition to non-thyroid organ involvement, presence of thyroid stimulating hormone receptor antibodies (TRAb) or increased uptake on a nuclear scan are diagnostic. Ultrasound typically shows a diffuse enlargement of the thyroid with increased vascularity, but up to 23% of patients are known to have thyroid nodules. Thyroid nodules carry a 4–6% risk ...

A 31 year-old woman is referred into the Endocrine clinic with a palpable mass in her right anterior neck that was found incidentally by her GP. She had no known past medical history, did not take any medications and had not noticed any dysphagia, neck pain, or compressive symptoms. On clinical exam, there was an enlarged thyroid with a 1.5-cm left-sided thyroid nodule that moved on swallowing. There was no palpable cervical lymphadenopathy. TSH was 2.5 mIU/l (0.29–5.1 mI...