Searchable abstracts of presentations at key conferences in endocrinology

ea0014p15 | (1) | ECE2007

Clinical significance of simultaneously determined serum interleukin-6, dehydroepiandrosterone and its sulphate levels in melanoma

Boldizsár Mariann , Vincze Borbála , Gilde Katalin , Bánfalvi Teodora , Fejos Zsuzsanna , Borbola Kinga , Kapuvári Bence , Liszkay Gabriella , Otto Szabolcs

Among well-known circulating melanoma markers 5-S-cysteinyldopa (5-SCD), a precursor of pheomelanin biosynthesis and S-100 beta (S-100B) are extensively investigated. Our earlier observations confirmed that serum concentration of 5-SCD and S-100B correlates well with the stages and progression of the disease. Interleukin-6 (IL-6) is a multifunctional inflammatory cytokine implicated in advanced stage of various diseases and tumour recurrence. Malignant melanoma cells are known...

ea0014p116 | (1) | ECE2007

Conjugated and unconjugated serum steroid hormone concentrations in relation to tumour receptor status in postmenopausal breast cancer patients

Vincze Borbála , Pommersheim Ferenc , Udvarhelyi Nora , Horváth Zsolt , Kapuvári Bence , Boldizsár Mariann , Köves István , Orosz Zsolt , Láng István

Human breast cancer tissue is able to concentrate estrogens. 17-beta-estradiol (E2) and estrone (E1) are produced locally through several mechanisms, e.g. from conjugated and unconjugated steroid hormones uptaken from the circulation. This study was aimed to investigate the correlation between endogenous serum sex steroid concentrations and tumour receptor status in postmenopausal breast cancer patients undergoing surgical intervention. The study involved 740 postmenopausal pa...

ea0014p315 | (1) | ECE2007

Significance of accurate serum thyroglobulin cut-off values in the postoperative follow-up of differentiated thyroid carcinoma

Boér András , Vincze Borbála , Sinkovics István , Keresztes Sándor , Kapuvári Bence , Boldizsár Mariann , Remenár Éva , Otto Szabolcs

The present study was undertaken to evaluate the diagnostic performance of a high-sensitive thyroglobulin (Tg) immunoradiometric assay (BRAHMS Tg-S) in the follow-up of papillary and follicular thyroid cancer patients treated with total/nearly total thyreoidectomy and radioiodine ablation therapy. During TSH suppression serum Tg concentration was measured 6 weeks prior to the radioiodine ablation (onT4-Tg before ablation) as well as 3 months following treatment (onT4–Tg a...