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ea0029p993 | Growth hormone IGF axis - basic | ICEECE2012

Clinical characteristics and outcome of acromegaly induced by ectopic secretion of GHRH: a French nationwide series of 21 cases

Garby L. , Caron P. , Claustrat F. , Chanson P. , Tabarin A. , Rohmer V. , Arnault G. , Bonnet F. , Chabre O. , Christin Maitre S. , Du Boullay H. , Murat A. , Nakib I. , Sadoul J. , Sassolas G. , Claustrat B. , Raverot G. , Borson Chazot F.

Context: Ectopic GHRH secretion is a rare cause of acromegaly described mainly in isolated case reports.Setting: From the registry of the sole laboratory performing plasma GHRH assays in France, we identified cases of ectopic GHRH secretion presenting with acromegaly between 1983 and 2008.Patients: In total, 21 patients aged 1477 years, from 12 French hospitals. Median GHRH was 548 ng/l (2709779)....

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ea0029p1362 | Pituitary Clinical | ICEECE2012

Markers of recurrence and long-term morbidity in craniopharyngioma

Gautier A. , Godbout A. , Grosheny C. , Tejedor I. , Coudert M. , Courtillot C. , Jublanc C. , De Kerdanet M. , Poirier J. , Riffaud L. , Sainte-Rose C. , VanEffenterre R. , Brassier G. , Bonnet F. , Touraine P.

Context: Craniopharyngiomas are often associated with an unfavorable prognosis but data on their long-term consequences are sparse.Objective: To identify markers of recurrence and factors associated with compromised social rehabilitation and altered quality of life (QoL) in a large cohort of patients with either childhood onset (CO) or adult onset (AO) craniopharyngioma.Methods: Retrospective analysis was performed for 171 patients...

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Endocrine Abstracts

Clinical characteristics and outcome of acromegaly induced by ectopic secretion of GHRH: a French nationwide series of 21 cases

Markers of recurrence and long-term morbidity in craniopharyngioma

BiosciAbstracts