Searchable abstracts of presentations at key conferences in endocrinology

ea0050cmw5.6 | Workshop 5: How do I. . . (2) | SFEBES2017

How do I manage.... myxoedema coma

Brooke Antonia

Myxoedema coma is a rare endocrine emergency with reported high mortality. Exact incidence is hampered by no clear consensus on its definition and the huge variability in its presentation. Most patients are not comatose, and have a form of severe, decompensated hypothyroidism. The common clinical features, including poor mentation, hypothermia, haemodynamic instability and lethargy, correlate poorly to degree of biochemical hypothyroidism. Early detection and identifying commo...

ea0050cmw5.6 | Workshop 5: How do I. . . (2) | SFEBES2017

How do I manage.... myxoedema coma

Brooke Antonia

Myxoedema coma is a rare endocrine emergency with reported high mortality. Exact incidence is hampered by no clear consensus on its definition and the huge variability in its presentation. Most patients are not comatose, and have a form of severe, decompensated hypothyroidism. The common clinical features, including poor mentation, hypothermia, haemodynamic instability and lethargy, correlate poorly to degree of biochemical hypothyroidism. Early detection and identifying commo...

ea0065ns1.2 | NICE – T3 | SFEBES2019

Health care professional & patient consultation – informed decision making

Brooke Antonia

Shared, informed decision making is a key component to high quality care in the NHS. This can occasionally be challenging through lack of time, lack of high-quality trial evidence to support treatment choices and financial limitations to treatment. Informed decision making includes open discussion of the risks and potential adverser consequences of treatment and alternatives. People with endocrine disorders often have symptoms that encompass both their psychological and physic...

ea0059mte10.2 | Service Improvements | SFEBES2018

The Society for Endocrinology peer review scheme

Brooke Antonia

Society for Endocrinology peer review is in its 16th year. In 2018 the format has been updated and single centre reviews are now being carried out. The catchment area of hospitals reviewed has varied from 280 000 to 2.5 million. A review helps to highlight a centre’s strengths and help focus on areas for development. It is a qualitative deep dive into a service which includes benchmarking against other similar services. The review is conducted by a team of clinical endocr...

ea0075d08 | Diabetes | EYES2021

Paraneoplastic hypoglycaemia: An insulin like growth factor-2 producing tumour

Cucknell Catherine , Brooke Antonia

Background: Insulin like growth factor-2 (IGF-2) has structural similarity to insulin1. In excess, IGF-2 can activate glucose metabolism so precipitating hypoglycaemia1.Case Presentation: Six days following her second dose of Doxorubicin and Olaratumab therapy for a pelvic sarcoma, HS presented with two successive days of acute confusion secondary to documented hypoglycaemia (blood sugars 2.0-3.1 mmol/l, 36-55.8 mg/dl). Despite treatment, she had recurre...

ea0065p87 | Bone and calcium | SFEBES2019

Investigations in preparation for surgically managed primary hyperparathyroidism

Bennett Robert , Brooke Antonia , Dunn Julie

Background: Recent NICE guidelines1 suggest imaging the parathyroid with ultrasound as first line prior to parathyroidectomy, MIBI as an alternative and surgical exploration if discordant. Investigation should also include a renal ultrasound and DEXA. This audit compares a single surgeon practice in one hospital to the guidelines.Methods and Results: All patients with a parathyroidectomy performed by a single surgeon between July 2016 and July...

ea0034p92 | Clinical practice/governance and case reports | SFEBES2014

An audit of clinical follow-up and management of adult patients with Turner's syndrome at the Royal Devon and Exeter

Whittle Elizabeth , Donohoe Mollie , Brooke Antonia

Introduction: Turners’ syndrome (TS) affects one in 2500 live births. Multiple comorbidities affect TS patients and recommendations for long-term management advocate annual review with a ‘checklist’ approach. This audit of current practice of a specialist TS clinic aims to identify gaps in patients’ management.Methods: A checklist of recommendations for health screening based on the National Turner’s Syndrome Guidelines was devel...

ea0069p66 | Poster Presentations | SFENCC2020

A case of sellar paraganlioma; rarest of the rare

Khan Haider , Muquit Samiul , Shivane Aditya , Brooke Antonia

Introduction: Paragangliomas are neuroendocrine tumours, usually found from the base of the skull to pelvis. They are extremely rare in the sellar and parasellar region which normally lacks paraganglion cells. We report a rare case of an incidental sellar paraganglioma.Case: A 66 years old female had progressive retinopathy and maculopathy of unclear cause since 2011. Lung nodules were seen on CT performed to exclude paraneoplastic retinopathy. 18F-FDG P...

ea0034p46 | Clinical biochemistry | SFEBES2014

High testosterone? Look again!

Babiker Tarig , Perry Mandy , McDonald Timothy , Brooke Antonia , O'Connor John

Three premenopausal patients presented with high isolated testosterone without symptoms of androgen excess or illicit drug use.Case 1: A 22-year-old female presented with daily vaginal bleeds having been on depot injections of progesterone with supplementary norethisterone. Testosterone was 14.5 nmol/l with suppressed gonadotrophins (LH <0.1 IU/l, FSH 0.2 IU/l, oestradiol <19 pmol/l). Her norethisterone was stopped. A repeat biochemical profile a...

ea0034p149 | Clinical practice/governance and case reports | SFEBES2014

Adrenocortical carcinoma, where's the delay?

Aziz Aftab , Dyer Rob , Dunn Julie , Goodman Andy , Brooke Antonia

Adrenocortical carcinomas are rare malignancies (incidence 1–2/one million). They present in a variety of ways and carry a poor prognosis. Prompt diagnosis and early intervention offers better outcome.We describe 5 cases of adrenocortical carcinoma to help identify and improve delays in their pathway of care. Five patients (four females and one male), age range 38–76 years, presented between September 2011 and April 2013. Three patients referre...