ea0035p578 | Endocrine tumours and neoplasia | ECE2014
Caplin Martyn
, Ruszniewski Philippe
, Pavel Marianne
, Cwikla Jaroslaw
, Phan Alexandria
, Raderer Markus
, Sedlackova Eva
, Cadiot Guillaume
, Wall Lucy
, Rindi Guido
, Langley Alison
, Blumberg Joelle
Introduction: Data demonstrating antiproliferative effects of somatostatin analogs (SSAs) in enteropancreatic NETs are limited; only one prospective trial so far has shown this for patients with midgut tumors and low hepatic tumor load (HTL). CLARINET is the first large phase 3, randomized, placebo-controlled trial evaluating such effects for the SSA lanreotide in patients with non-functioning enteropancreatic NETs.Methods: Patients who had well/moderate...