Searchable abstracts of presentations at key conferences in endocrinology

ea0073ep145 | Pituitary and Neuroendocrinology | ECE2021

A case of Cushing syndrome misdiagnosed as treatment with antiepileptic drug

Mehmet Sözen , BerrinÇetinarslan , Zeynep Cantürk , Selek Alev , Gezer Emre , Damla Köksalan

IntroductionThe most common causes of pseudo Cushing syndrome are alcoholism, chronic kidney disease, neuropsychiatric diseases, pregnancy, uncontrolled diabetes, and drugs. We present a patient who was operated on suspected Cushing syndrome based on abnormal results in overnight dexamethasone suppression tests.Case presentationA 49-year-old female patient was referred to our clinic for reoperation due to per...

ea0070aep650 | Pituitary and Neuroendocrinology | ECE2020

Differentiation of Insulinoma from accessory spleen by 99mTc-labelled heat-denaturated red blood cell scintigraphy

Gezer Emre , Çetinarslan Berrin , Karakaya Dilek , Cantürk Zeynep , Selek Alev , Sözen Mehmet , İșgören Serkan

Introduction: Neuroendocrine tumors (NETs) are rare tumors harboring overexpression of somatostatin receptors (SSTRs) on their cell membrane. Gallium 68-tetraazacyclododecane tetraacetic acid-octreotate (68Ga-DOTATATE) positron emission tomography/computed tomography (PET/CT) is an important imaging modality in diagnosis and staging of NETs. Because some organs such as spleen, adrenal glands and liver physiologically express SSTR, it might be challenging to distinguish some pa...

ea0070aep14 | Adrenal and Cardiovascular Endocrinology | ECE2020

Comparability of steroid hormone measurement among 9 European laboratories using liquid chromatography-tandem mass spectrometry (LC-MS/MS): Impact of the blood derivative and of calibration

Fanelli Flaminia , Mezzullo Marco , Nardi Elena , Cantù Marco , Lindner Johanna M , Peitzsch Mirko , Hawley James M , Bruce Stephen J , Heijboer Annemieke C , Ackermans Mariette T , Van den Ouweland Jody , Koeppl Daniel , Eisenhofer Graeme , Rauh Manfred , Keevil Brian , Vogeser Michael , Pagotto Uberto

Background: LC-MS/MS is recommended for accurately measuring circulating steroids. However, laboratories using LC-MS/MS adopt various pre-analytical and analytical strategies, and little is known about comparability of results. Whether different blood derivatives impact LC-MS/MS measurements is unclear, and the benefit of unifying the calibration system among laboratories was not tested.Aim: Comparisons of LC-MS/MS measurements of circulating aldosterone...