Endocrine Abstracts

Background: The importance of carcinoembryonic antigen (CEA) assessment in the evaluation of medullary thyroid carcinoma is well known. The role of CEA in the assessment of other neuroendocrine tumors (NET) is not clear. We aimed to evaluate a possible correlation between CEA measurements and the aggressivity of NETs.Methods: We evaluated 56 (36 women) NETs followed in a tertiary center (23 gastrointestinal, 12 pancreatic, 10 pulmonary, 7 without primary...

Introduction: The new tool FRAX indicated risk of fracture, using or not DXA which is the golden standard for osteoporosis diagnosis.Aim: We analyzed the lumbar DXA correlations with 10-year fragility fracture risk probability.Material and method: A cross sectional study in postmenopausal women was designed. They were osteoporosis free at baseline; none of them has previously been treated for osteoporosis. The anamnesis, the anthro...

Introduction: The fat mass (FM) is assessed by DXA, magnetic resonance, etc. One of the most accessible methods for current practice is bioimpedance.Aim: We analyzed FM based on bioimpedance and fragility fracture risk.Material and method: This is a transversal study in women, admitted at C.I.Parhon National Institute of Endocrinology, Bucharest, Romania. The inclusion criteria were women in menopause. The exclusion criteria were p...

Introduction: Acromegaly is a rare, chronic endocrinopathy, that results from persistent hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor 1 (IGF1). It is well known that GH excess has multisystemic effects throughout the body, but its interaction with the immune system has only been suggested in the last few decades. This prompted us to explore the frequency of autoimmune disorders in a retrospective acromegaly cohort....

Background: BMAD is defined as development of multiple large nodules, >1 cm diameter, with bilateral involvement of the adrenal glands. It is typically associated with endogenous Cushing’s syndrome (CS) and occurs in adults, in the 4th-7th decade of life.Aim: To describe the clinical presentation, the biochemical peculiarities and the management of 71 patients diagnosed with BMAD in a tertiary endocrinology centre.Results:...