Searchable abstracts of presentations at key conferences in endocrinology

ea0032p13 | Adrenal cortex | ECE2013

Detection of circulating tumor cells in adrenocortical carcinoma: a monocentric preliminary study

Poli Giada , Pinzani Pamela , Scatena Cristian , Salvianti Francesca , Corsini Elisa , Canu Letizia , Piccini Valentina , Nesi Gabriella , Mannelli Massimo , Luconi Michaela

Objective: Adrenocortical carcinoma (ACC) is a rare malignancy, whose prognosis is mainly dependent on the stage at diagnosis. The identification of disease-associated markers representing solid biomarkers for early diagnosis and drug monitoring is mandatory to improve survival rate and life quality of patients. CTC are tumor cells originating from primary tumor or metastases. The tumor-induced angiogenesis and invasion allow aggressive tumors to release CTC into blood stream ...

ea0032oc4.3 | Adrenal | ECE2013

Prognostic factors of advanced unresectable by stage III and IV ENS@T adrenocortical carcinomas (ACC)

Libe Rossella , Borget Isabelle , Ronchi Cristina , Terzolo Massimo , Haaf Michaela , Laino Federica , Kherkhof Thomas , Corsini Elisa , Tabarin Antoine , Chabre Olivier , De la Fouchardiere Christelle , Niccoli Patricia , Caron Philippe , Mannelli Massimo , Haak Harm , Beuchlein Felix , Bertherat Jerome , Berruti Alfredo , Fassnacht Martin , Baudin Eric

Introduction: The prognosis of stages III–IV ACC patients is dismal. The 5-year survival of stage IV ACC ranges between 0 and 13% and no prognostic study has focused on stage III, yet. Several reports suggest a greater heterogeneity of advanced ACC prognosis that initially thought.Aim: The primary objective of our study was to analyse the prognostic factors of overall survival of the subgroup of advanced unresectable stage III–IV ACC patients c...