Searchable abstracts of presentations at key conferences in endocrinology

ea0038p250 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015

Lifelong exposure to sewage sludge chemicals causes proteome-wide and sex-specific disturbances in the liver

Filis Panagiotis , Eaton-Turner Emily , Bellingham Michelle , Amezaga Maria , Mandon-Pepin Beatrice , Evans Neil , Sharpe Richard , Cotinot Corinne , Rhind Stewart , O'Shaughnessy Peter , Fowler Paul

Introduction: A complex cocktail of endocrine-disrupting and other chemicals is ubiquitous in the modern environment. Exposure to such chemicals contributes to diseases including metabolic syndrome and infertility. The liver is the primary defence organ against xenotoxicants, but also the source of major of plasma proteins, and growth factors/hormones.Aim: To understand how chronic exposure to complex mixtures of chemicals at human and environmentally re...