Endocrine Abstracts

Introduction: Pituitary apoplexy is a rare complication in 2%-12% of pituitary adenomas, due to sudden hemorrhage or infarction. Patients with signs of meningeal irritation, important visual field defects, ocular paresis, decreased unilateral or bilateral visual acuity or altered consciousness are treated by neurosurgical intervention, while patients without these signs could be managed conservatively.Aim: To present a series of 4 cases with pituitary ap...

Background: Pituitary adenomas (PA) are slow-growing, benign intracranial tumors. Rarely, they can be histologically and clinically aggressive.Aim: To present a case of corticotroph PA with aggressive behavior following a long indolent interval after the initial surgery.Case presentation: A 47 years old female presented in Nov 2007 with right temporal hemianopsia and left eye blindness, associating type 2 DM and severe mixed dyslip...

Background: Aggressive PitNETs require multidisciplinary management. Cushing’s disease (CD) poses specific challenges regarding biochemical control and management of complications.Aim: To describe management of a series of aggressive corticotroph PitNETs.Patients: Six patients (2F/4M, 46-75 yo), managed through the pituitary MDT.Results: At diagnosis all patients had overt CD due to macroPitNets (2-3.8 c...