Searchable abstracts of presentations at key conferences in endocrinology

ea0063oc14.2 | Sex Hormones | ECE2019

The effect of testosterone therapy on serum oestradiol levels in transgender men

Defreyne Justine , Aers Xavier-Philippe , Daphne Fisher Alessandra , Schreiner Thomas , Den Heijer Martin , T'Sjoen Guy

Background: Testosterone therapy in transgender men (TM) is aimed at achieving serum testosterone levels in the male reference range. It remains unknown if serum oestradiol levels in TM should be evaluated and/or adjusted. Although reported serum oestradiol levels in TM are variable in the current literature, these values may be affected through two possible mechanisms: serum oestradiol levels may increase through aromatization of exogenous testosterone, while the effects of e...

ea0049ep1032 | Pituitary - Clinical | ECE2017

Does cyproterone acetate therapy contribute to the observed elevation in serum prolactin levels in trans women?

Defreyne Justine , Nota Nienke , Perreira Cecilia , Thomas Schreiner , Daphne Fisher Alessandra , Guy T'Sjoen

Objective: Hormonal treatment in trans women (MtF transgender persons) in Europe usually consists of estrogens and anti-androgens, e.g. cyproterone acetate (CPA). After initiation of cross-sex hormone therapy, an elevation in serum prolactin levels is frequently observed in trans women, which was previously attributed to estrogen agents. This analysis evaluates whether CPA contributes to the elevation of prolactin in trans women receiving cross-sex hormones.<p class="abste...

ea0032p676 | Male reproduction | ECE2013

Two unconventional risk factors for major adverse cardiovascular events in subjects with sexual dysfunction: low education and reported partner's hypoactive sexual desire in comparison with conventional risk factors

Rastrelli Giulia , Corona Giovanni , Daphne Fisher Alessandra , Mannucci Edoardo , Maggi Mario

Introduction: The classification of subjects as low or high cardiovascular (CV) risk is usually performed by risk engines, based upon multivariate prediction algorithms. However, their accuracy in predicting major adverse CV events (MACE) is lower in high-risk populations, since they take into account only conventional risk factors.Aim: To evaluate the accuracy of Progetto Cuore risk engine in predicting MACE in subjects with erectile dysfunction (ED), a...

ea0032p677 | Male reproduction | ECE2013

‘It takes two to tango’: the relational domain in a cohort of subjects with erectile dysfunction (ED)

Boddi Valentina , Rastrelli Giulia , Corona Giovanni , Daphne Fisher Alessandra , Forti Gianni , Maggi Mario

Introduction: The relational domain of erectile dysfunction (ED) is difficult to investigate in a clinical setting. We developed and validated SIEDY, a 13-item structured interview, which assesses, beside the organic (Scale1) and intra-psychic (Scale 3) domains, also the relation one (Scale 2). We previously established a pathological threshold for SIEDY Scale 1 and 3.Aim: To identify a pathological threshold of SIEDY Scale 2.Metho...