Searchable abstracts of presentations at key conferences in endocrinology

ea0017p44 | (1) | BSPED2008

Clinical challenges in children with Type I diabetes mellitus aged less than 6 years old in a UK region

Anderson Y , De Palma A , Widmer B , Ong K , Acerini C

Objectives: To assess current clinical practice in children aged 0–5.99 years with Type I Diabetes Mellitus (T1DM).Methods: All paediatric diabetes centres (n=17) within a single UK region were asked to provide retrospective data for the year ending 01/12/07. 15 (88%) centres responded and provided data for each child on presentation, initial and current insulin regimens. Outcome measures were HbA1c, and acute hospital admissions post-diagnos...

ea0041gp230 | Thyroid Cancer (1) | ECE2016

Analysis of germline VEGF-A SNPs allows the identification of a subgroup of ATA low-intermediate risk DTC (differentiated thyroid cancer) patients with poor probability to develop recurrences

Marotta Vincenzo , Sciammarella Concetta , Capasso Mario , Testori Alessandro , Gambardella Claudio , Grasso Marica , Rubino Manila , De Palma Maurizio , Grazia Chiofalo Maria , Pivonello Claudia , Pivonello Rosario , Santini Luigi , Pezzullo Luciano , Colao Annamaria , Faggiano Antongiulio

Introduction: Constitution of new blood vessels is crucial for cancer self-maintenance and progression. Neo-angiogenesis may be affected from hereditary traits, namely the presence of SNPs (single nucleotide polymorphisms) of genes involved in its regulation. VEGF-A represents the main regulator of angiogenesis. Germline SNPs of the VEGF-A gene have been associated to outcome of several cancers, but no data exist about differentiated thyroid cancer (DTC).<p class="abstext"...