Endocrine Abstracts

Objective: We developed a novel dual-component molecular assay as an ancillary method to improve clinical decision-making in patients with cytologically indeterminate thyroid nodules. The assay includes next-generation sequencing (NGS) based detection of mutations in 23 thyroid cancer related genes and digital polymerase chain reaction (dPCR) evaluation of the expression levels of a microRNA strongly associated with thyroid cancer. The method was designed as a “rule-out&#...

Background: The COVID-19 outbreak in Italy forced the health system to cancel all non-urgent outpatient activities, to avoid further spreading of the disease inside the healthcare facilities. At our institution, for cancer patients the hospital allowed treatments and consultations: the medical team, however, identified patients whose procedures could be postponed. Even after May 2020, the capacity for non-urgent thyroid surgeries was reduced. These events enhanced our efforts ...