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44th Annual Meeting of the European Thyroid Association (ETA) 2022

Brussels, Belgium
10 Sep 2022 - 13 Sep 2022

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Oral Presentations

Oral Session 12: Nodules and Diagnostic

ea0084op-12-59 | Oral Session 12: Nodules and Diagnostic | ETA2022

Autonomously functioning thyroid nodules present intermediate malignancy risk according to european thyroid imaging and reporting data system; a comprehensive clinical, cytological and molecular characterization

Kyrilli Aglaia , tacelli nunzia , Lebrun Laetitia , Salmon Isabelle , Russ Gilles , Moreno-Reyes Rodrigo , Corvilain Bernard

Objectives: To systematically characterize autonomously functioning thyroid nodules (AFTN) by clinical, biological and imaging methods, cytology and histology when indicated.Design: Prospective, single-center study conducted from March 2018 until September 2021, in 901 consecutive patients with 67 AFTN evaluated.Methods: Enrolled patients underwent 99mTcO4 scintigraphy evaluation of thyroid function, ultrasound (US) usin...

ea0084op-12-60 | Oral Session 12: Nodules and Diagnostic | ETA2022

Population study on thyroid nodule ultrasound (TUS) reports quality with adherence to guidelines

Yang Hu Xun , Wu Jiahui , Seal Paula , Ghaznavi Sana , Symonds Christopher , Kinnear Susan , Paschke Ralf

Objectives: To date, there has been no population-wide data looking at the adherence to published TUS reporting guidelines for thyroid nodule malignancy risk assessment. In our health care region in 2018, two radiology groups worked closely with endocrinologists to improve the quality of their TUS reports by adhering to the 2015 ATA or the 2017 TIRADS guidelines. We aim to present the improvement in TUS reports quality with these dedicated changes.Method...

ea0084op-12-61 | Oral Session 12: Nodules and Diagnostic | ETA2022

Comparison of accuracy of 18F-fluorocholine PET-CT and PET/MR to 99MTC-sestamibi for the localization of hyperfunctioning parathyroid tissue in hyperparathyroidism

Mathey Celine , Ortansa-Irina Vierasu , Caroline Keyzer , Isabelle Delpierre , Nicola Trotta , Absil Julie , Lacroix Simon , Corvilain Bernard , Goldman Serge , Moreno-Reyes Rodrigo

Objectives: The aim of this prospective study was to compare the diagnostic performance of 99mTc-sestaMIBI SPECT scintigraphy (sestaMIBI), 18F-fluorocholine PET/CT or PET/MR (FCH) for preoperative localization of hyperfunctioning parathyroid gland.Materials and Methods: 60 patients with biochemical evidence of primary (n=57) or tertiary (n=3 kidney transplanted patients) hyperparathyroidism were imaged prospectivel...

ea0084op-12-62 | Oral Session 12: Nodules and Diagnostic | ETA2022

Progressive diastolic dysfunction in survivors of pediatric differentiated thyroid carcinoma

Reichert Antoinette , Nies Marloes , tissing wim , Muller Kobold Anneke , Klein Hesselink Marielle , Brouwers A.H. , Havekes Bastiaan , van den heuvel-eibrink marry , van der pal helena , plukker john , Van Santen Hanneke , corssmit eleonora , Teodora Netea-Maier Romana , Peeters Robin , van Dam Eveline , burgerhof johannes , van der Meer Peter , bocca gianni , Links Thera

Background: Pediatric differentiated thyroid cancer (DTC) has an excellent prognosis, but has unknown late effects of treatment. Initial cardiac evaluation showed subclinical diastolic dysfunction in 20% of adult survivors. In this follow-up study, we determined the clinical course of this finding.Methods: This multicenter study, conducted between 2018 and 2020, re-evaluated survivors 5 years after the first evaluation. The primary endpoint was echocardi...

ea0084op-12-63 | Oral Session 12: Nodules and Diagnostic | ETA2022

Real-world performance of a novel dual-component molecular assay in cytologically indeterminate thyroid nodules: a single institutional experience

Sponziello Marialuisa , Grani Giorgio , Verrienti Antonella , Pecce Valeria , Del Gatto Valeria , Bosco Daniela , Ascoli Valeria , Filetti Sebastiano , Durante Cosimo

Objective: We developed a novel dual-component molecular assay as an ancillary method to improve clinical decision-making in patients with cytologically indeterminate thyroid nodules. The assay includes next-generation sequencing (NGS) based detection of mutations in 23 thyroid cancer related genes and digital polymerase chain reaction (dPCR) evaluation of the expression levels of a microRNA strongly associated with thyroid cancer. The method was designed as a “rule-out&#...