Searchable abstracts of presentations at key conferences in endocrinology

ea0056p831 | Pituitary - Clinical | ECE2018

Two-dimensional speckle tracking echocardiography showed a slight impairment of left ventricular deformability in acromegalic patients at diagnosis and during follow-up

Urbani Claudio , Fabiani Iacopo , Siciliano Valeria , Cappellani Daniele , Mantuano Michele , Pugliese Nicola Riccardo , Marcocci Claudio , Di Bello Vitantonio , Bogazzi Fausto

Introduction: Acromegalic heart disease is characterized by concentric left ventricular (LV) hypertrophy and impaired LV function. Speckle tracking echocardiography (STE) allows a non-invasive and reproducible study of myocardial strain, a marker of cardiac deformability and early ventricular systolic dysfunction.Objectives: The aims of the study are: 1) evaluation of STE parameters in acromegalic patients at diagnosis and during the follow-up; 2) apprai...

ea0041ep883 | Pituitary - Clinical | ECE2016

Disease activity and lifestyle influence the occurrence of cardiovascular risk factors and cardiovascular events in acromegaly

Sardella Chiara , Cappellani Daniele , Urbani Claudio , Manetti Luca , Marconcini Giulia , Tomisti Luca , Lupi Isabella , Rossi Giuseppe , Scattina Ilaria , Lombardi Martina , Di Bello Vitantonio , Marcocci Claudio , Martino Enio , Bogazzi Fausto

Context: Acromegalic patients have a high-risk cardiovascular profile. However, the determinants of cardiovascular risk factors and major cardiovascular events (MACE), which may develop after diagnosis of acromegaly, are not fully understood.Objectives: To identify the predictors for systemic comorbidities and MACE, after diagnosis of disease. The role of therapy for acromegaly on the occurrence of such complications was also evaluated.<p class="abst...