Endocrine Abstracts

Introduction: Von Hippel-Lindau (VHL) disease is an autosomal dominant disorder characterized by formation of tumors and cysts in various organs. Renal cancer and central nervous system angiomas (whose frequencies in VHL disease are estimated for 70% and 76% respectively) are considered main prognostic factors, with renal cancer being the most common cause of death. Neuroendocrine tumors of the pancreas occur in only 10 to 20% of VHL patients and are benign in the majority of ...

Adrenocortical carcinoma is an aggressive tumor of endocrine system with an annual incidence of 1–2 cases per million. The most significant prognostic factors are tumor size, disease stage at the time of putting the diagnosis and treatment method. Advanced age of the patient, and hormonal activity of the cancer are also related to poor prognosis.Materials and methods: In our study we collected data of 12 patients who were treated in Endocrinology Cl...