Searchable abstracts of presentations at key conferences in endocrinology

ea0078OC8.5 | Oral Communications 8 | BSPED2021

Permanent neonatal diabetes due to KCNJ11 mutation: early successful transition to Glibenclamide and stable glucose profile with multiple daily dosing

Hawton Katherine , Adams Rebekah , Dustan Emily , Giri Dinesh

Introduction: Neonatal diabetes (ND) usually presents before 6 months of age and 50% of cases are transient and 50% permanent with more than 20 known genetic causes. Early recognition and urgent genetic testing are important to enable appropriate, precise treatment. Mutations in KCNJ11 cause ND responsive to glibenclamide, alleviating the need for insulin administration, but there are limited reports of early successful transition.Case: This inf...